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Just a reminder to all you guys to wrap up BBC Health reporter, BBC News Gonorrhoea rates had been declining in recent yearts the UK until a slight increase in 2010 Continue reading the main story Related Stories Gonorrhoea drugs resistance fear Gonorrhoea down as herpes rises UK doctors are being told the antibiotic normally used to treat gonorrhoea is no longer effective because the sexually transmitted disease is now largely resistant to it. The Health Protection Agency says we may be heading to a point when the disease is incurable unless new treatments can be found. For now, doctors must stop using the usual treatment cefixime and instead use two more powerful antibiotics. One is a pill and the other a jab. The HPA say the change is necessary because of increasing resistance. Untreatable strains Tests on samples taken from patients and grown in the laboratory showed reduced susceptibility to the usual antibiotic cefixime in nearly 20% of cases in 2010, compared with just 10% of cases in 2009. This presents the very real threat of untreatable gonorrhoea in the future” Prof Cathy Ison HPA As recently as 2005, no gonorrhoea bacteria with reduced susceptibility to cefixime could be found in the UK. The bacterium that causes the infection - Neisseria gonorrhoeae - has an unusual ability to adapt itself and has gained resistance, or reduced susceptibility, to a growing list of antibiotics - first penicillin itself, then tetracyclines, ciprofloxacin and now cefixime. The World Health Organization recommends that the first-line antibiotic used is changed when treatment failure in patients reaches 5%. But for cefixime, the change is being made pre-emptively, owing to the alarming rise in resistance that is emerging. Prof Cathy Ison, a gonorrhoea expert at England's HPA, said: "Our lab tests have shown a dramatic reduction in the sensitivity of the drug we were using as the main treatment for gonorrhoea. This presents the very real threat of untreatable gonorrhoea in the future. "We were so worried by the results we were seeing that we recommended that guidelines on the treatment of gonorrhoea were revised in May this year, to recommend a more effective drug. "But this won't solve the problem, as history tells us that resistance to this therapy will develop too. In the absence of any new alternative treatments for when this happens, we will face a situation where gonorrhoea cannot be cured." She said patients who refuse the jab will be offered oral antibiotics instead. She added: "This highlights the importance of practising safe sex, as, if new antibiotic treatments can't be found, this will be only way of controlling this infection in the future." After genital chlamydia, gonorrhoea is the second most common bacterial sexually transmitted infection in the UK. According to HPA figures, there were 16,145 new diagnoses of gonorrhoea in 2010, a 3% increase on 2009 when there were 15,606. More on This Story Related StoriesGonorrhoea drugs resistance fear 11 JULY 2011, HEALTH Gonorrhoea down as herpes rises 24 JULY 2009, HEALTH Related Internet linksHPA - Gonorrhoea Around the BBCBBC Health: Gonorrhoea

 

Cheers Tilacno1

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This has been discussed ad nauseam here once and the other boards. Gonorrhoea is not resistant to the Cephalasporin which is the gold stadard, first line treatment. It has been resistant for all practical purposes for a while to Quinilones and in Asia longer than other locations, so the ol' Cipro will not be effective. NB Cipro is still your first line for the scours, shits, trots, Montezuma's Revenge, etc. and Prostatitis.

 

Wrap your willy or if you are exclusive both get a test for the clap , it's only about $5-6. Add Chlamyida too. The lab I've mentioned before off of 3rd Road and near Soi 17 3rd Road will test for Gonorrhoea , Chlamydia, HIV (quick) and VDRL (Syphilis) and Hep B for THB$600 with results same day. The Quick HIV isn't perfect but it is a good sign when negative.

 

Ceftriaxone still works as does Cefixime. Note the addition of Azithromycin is not for gonorrhoea at all but for Chlamydia which is almost (but not) always co-infecting in cases of gonorrhoea .

 

What the HPA still says is:

 

Current Antimicrobial Prescribing Policy

 

Therapy for gonorrhoea is often given before the susceptibility of the infecting organism is known, and GRASP has both informed and recommended changes to national guidelines to ensure that more the 95% of infections respond to first-line therapy. Current treatment-guidelines recommend a cephalosporin: Ceftriaxone 500mg IM as a single dose with Azithromycin 1g oral as a single dose and Cefixime 400mg oral as a single dose as an alternative if an intramuscular injection is contra-indicated or refused by the patient . Fluoroquinolones such as ciprofloxacin or ofloxacin are no longer recommended as first-line therapies for gonococcal infections.

Edited by ricktoronto
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